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A New Technology for Extending Youth

Hormonal Youth in Women

Today, more and more women are thinking about how to preserve hormonal health, prevent menopause, and prolong youth. The period of perimenopause and menopause is associated not only with changes in appearance but also with an increased risk of cardiovascular disease, dysfunction of the musculoskeletal system, and a general decline in quality of life.
In this article, we will discuss a new technology that opens unique opportunities for maintaining youth during menopause.

This technology is not just another medical method, but a true breakthrough in the field of extending female youth.
Innovation. The use of autotransplantation of ovarian tissue to preserve hormonal health is a method with no analogues in classical gynecology and anti-aging medicine. It is based on the latest advances in cryopreservation and transplantation technologies.

Professor Nikolai Rukhlyada: The Science of Sustained Youth

The developer of this method is Professor Nikolay Nikolaevich Rukhlyada — Doctor of Medical Sciences, Professor, Head of the Department of Obstetrics and Gynecology at the St. Petersburg State Pediatric Medical University.

•  Over 25 years of experience in medicine  
•  Presidential Scholar of the Russian Federation, laureate of the international Russ & Joan Zajtchuk Award  
•  Member of FIGO (International Federation of Gynecology and Obstetrics)  
•  Author of more than 10 patents and numerous scientific publications  
•  Expert in reproductive medicine, transplantation technologies, and tissue cryopreservation

The technology has received patents in both Russia and the United States, which confirms its uniqueness and potential.
Профессор Николай Рухляда: Наука на страже вашей молодости
Why Standard HRT is Not Enough
01
In modern medicine, we are able to compensate for the lack of estrogen and progesterone with synthetic medications. However, ovarian function is not limited to these two hormones.
02
Mass spectrometry analysis of ovarian tissue has revealed more than 140 metabolites that had not previously been described. Their exact names and functions are still under research, but it is clear that they play important roles — from fine-tuning metabolism to enhancing the effects of classical sex hormones.
03
In nature, there are no “redundant” molecules — each one has meaning for preserving a woman’s health and youth.

The Essence of the New Technology

The method is based on the cryopreservation of a woman’s own ovarian tissue at an age when the ovary is still functionally active (optimally — before 35 years old).

Tissue collection is performed laparoscopically. This procedure does not accelerate menopause: studies confirm that women with one ovary enter menopause at the same age as those with two. Only about 15% of the volume of one ovary is recommended for preservation.
Histological control — the tissue is checked at the cellular level (an additional early diagnostic tool for possible ovarian pathology).
Preparation of the product — approximately 20 doses of biopreparation are obtained from the tissue.
Cryopreservation — the product is frozen and stored in liquid nitrogen.
Application — during perimenopause, microinjections with the autologous preparation or autotransplantation are performed.

Thus, a woman receives not only the familiar hormones (estrogen and progesterone) usually delivered by menopausal hormone therapy (MHT), but also the entire unique spectrum of ovarian metabolites, which menopause deprives the body of.

Effect and Duration
Twenty doses of the preparation are sufficient for approximately 10–12 years of extended hormonal youth. This means the new technology can prolong youth and delay the negative manifestations of menopause for at least a decade.
Patient Selection Criteria
•  No oncological diagnosis at the time of tissue collection  
•  FSH level below 30  
•  Preferably under the age of 35 for the initial tissue collection
Scientific Basis of the Method
The methodology is based on oncofertility technologies. Previously, ovarian tissue cryopreservation was used in young women with cancer who required chemotherapy. After re-implantation, their hormonal function was restored, and in some cases, ovulation and pregnancy occurred.Today, this approach has been adapted for maintaining hormonal health and prolonging youth in menopause.
Where the Technology is Available
The method was first applied in Russia by Professor Nikolay Nikolaevich Rukhlyada and in the United States at the Fertility Preservation Clinic of Professor Kutluk Oktay in New York. The original technology is patented in both the USA and Russia.

Safety of the Procedure

One of the main concerns for women when discussing new medical technologies is safety.

No risk of premature menopause. Scientific data confirm that women with only one ovary enter menopause at the same age as those with two. Thus, harvesting a small portion of tissue does not accelerate reproductive aging.
Minimally invasive. The tissue is collected laparoscopically — a low-trauma surgery performed through small incisions with rapid recovery.
Guaranteed quality control. Every portion of tissue undergoes histological examination before cryopreservation, eliminating the risk of using compromised material.
Autotransplant. The woman’s own tissue is used, completely excluding the risk of rejection, allergic reactions, or infection. The body recognizes it as “self.”
Global practice. Similar technologies have been used for decades in oncofertility to preserve reproductive function in women undergoing chemotherapy. This rich experience forms the foundation for the new method of prolonging hormonal youth.
Long-term safety. Cryopreservation of tissues is internationally recognized as a safe method for long-term storage of biological material, supported by thousands of successful cases.

Thus, this technology is maximally safe and not only poses no threat to hormonal health but, on the contrary, allows women to preserve youth during perimenopause and extend it for years.

Consultation and Support
Our clinic is an official partner and ambassador of the method. We provide:
•  Initial patient selection  
•  Consultations (including remote consultations for non-local patients)  
•  Assistance with visas for international patients, transfers, and accommodation booking  
•  Support at every stage of the procedure  
•  English-language assistance for international patients
If you are considering how to prevent menopause, prolong youth, and preserve hormonal health — book a consultation with us.

Hormonal youth in women is not a myth. Modern technologies allow not only compensation for the lack of classical hormones but also replenishment of the entire spectrum of unique ovarian metabolites.

This method gives women the chance to extend youth, prevent early menopause, and preserve quality of life for decades.

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